Aniracetam

Aniracetam (1-Anisoyl-2-pyrrolidinone) is a fat soluble analog of the brain supplement Piracetam (2-oxo-1-pyrrolidine acetamide). Sold in Europe under the name Ampamet.

While it shares many of Piracetam’s effects on the brain it has two main unique advantages Piracetam does not have: 1. Being fat soluble it has far better penetration into the brain through the blood brain barrier and is longer lasting. 2. It is a potent stimulator of the brain’s Glutamate AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptors.

AMPA receptor research is considering an exciting development in studying and enhancing Cognition. Such compounds that effect AMPA receptors are called Ampakines.

• Positive allosteric modulator of AMPA receptors (Ampakine)
• Enhances glutamatergic neurotransmission, long term potentiation, synaptic transmission, neurotrophin expression, and impulsivity.
• Potentiates alpha 4 beta 2-type nicotinic acetylcholine receptors
• Improves memory & facilitates dual dopaminergic/serotonergic transmission
• Regulates calcium/calmodulin-dependent protein kinase (CaMKII)
• Elevates memory consolidation
• Modulates Serotonin 5-HT2A and dopamine D2 receptors
• Reduces stress
• Improves Cerebral Glucose Metabolism